Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234118 | 0.86 | DHODH (0.41) | KDM1AMAOBDHODHMAOACTSC | |
| SCHEMBL5236715 | 0.83 | KDM1A (0.39) | KDM1AMAOBDHODHMAOAKMO | |
| SCHEMBL5234475 | 0.83 | MGLL (0.48) | MAPTSLC6A7SMN1; SMN2 | |
| SCHEMBL5234121 | 0.79 | DHODH (0.39) | KDM1AMAOBDHODHMAOACTSC | |
| SCHEMBL5230452 | 0.79 | SLC6A7 (0.49) | KDM1AMAOBDHODHCTSCKMO | |
| SCHEMBL5233237 | 0.73 | SMN1; SMN2 (0.44) | MAPTHPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL5232200 | 0.72 | SLC6A7 (0.42) | KDM1AMAOBMAOAMAPTHPGD | |
| SCHEMBL594736 | 0.70 | LMNA (0.50) | KDM1AMAOBMAOAMAPTHPGD | |
| SCHEMBL5231133 | 0.70 | CNR2 (0.51) | MAPTLMNACNR2SMN1; SMN2 | |
| SCHEMBL595155 | 0.70 | ALDH1A1 (0.55) | MAPTHPGDLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |