Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558397 | 0.81 | SMN1; SMN2 (0.47) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL5237725 | 0.77 | MEN1 (0.47) | RECQLHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5231836 | 0.74 | STING1 (0.38) | RECQLSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL7313747 | 0.74 | STING1 (0.38) | RECQLSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL5272194 | 0.72 | AVPR1A (0.54) | AVPR2AVPR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7319409 | 0.71 | AVPR2 (0.66) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL19078673 | 0.69 | L3MBTL1 (0.48) | RAB9ASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL19064489 | 0.68 | L3MBTL1 (0.46) | RAB9ASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL19454365 | 0.68 | ALDH1A1 (0.43) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL20618436 | 0.67 | PGR (0.38) | SMN1; SMN2HPGDSTING1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804440-B1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2007-12-19 | — | — | EP | disclosed |
| US-5532235-A | TO TREAT EXCESS RENAL REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |