Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234716 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL5238192 | 0.89 | CYP2C19 (0.37) | ALDH1A1MEN1KMT2ARAB9AHTT | |
| SCHEMBL5238652 | 0.88 | HSD17B10 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL5232239 | 0.88 | SCD (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5239098 | 0.88 | MEN1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5234786 | 0.87 | FFAR4 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5235809 | 0.87 | MAPT (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5232337 | 0.85 | LMNA (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5235446 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5236884 | 0.84 | SLC6A7 (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |