Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237317 | 0.76 | ADRB1 (0.55) | ADRB1CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL20907901 | 0.74 | ADRB1 (0.55) | ADRB1CHRNB2CHRNA4SIRT6HTR3E | |
| SCHEMBL14922258 | 0.74 | ADRB1 (0.53) | ADRB1SIRT6HTR3EHTR3BHTR3A | |
| SCHEMBL12298703 | 0.73 | ADRB1 (0.50) | ADRB1CHRNB2CHRNA4SIRT6HTR3E | |
| SCHEMBL12298581 | 0.73 | ADRB1 (0.50) | ADRB1CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL82301 | 0.71 | ADRB1 (0.85) | ADRB1CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL5236468 | 0.71 | CHRNB2 (0.48) | ADRB1CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL9630200 | 0.70 | DRD2 (0.49) | SIGMAR1 | |
| SCHEMBL5232578 | 0.70 | CETP (0.48) | ADRB1CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL5237023 | 0.70 | CHRNB2 (0.54) | ADRB1CHRNB2CHRNA4HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |