Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521919 | 0.76 | DRD2 (0.59) | DRD2SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9631745 | 0.75 | OPRL1 (0.64) | SIGMAR1OPRL1 | |
| SCHEMBL27977483 | 0.73 | DRD2 (0.59) | DRD2SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL11014683 | 0.72 | NOS3 (0.37) | — | |
| SCHEMBL8759961 | 0.72 | ESR1 (0.42) | SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL5462404 | 0.72 | DRD2 (0.54) | DRD2SLC6A2SLC6A4SIGMAR1OPRM1 | |
| SCHEMBL5236809 | 0.70 | ADRB1 (0.44) | SIGMAR1 | |
| SCHEMBL13898233 | 0.70 | DRD2 (0.56) | DRD2SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL613058 | 0.70 | DRD2 (0.66) | DRD2SLC6A2SLC6A4SIGMAR1OPRM1 | |
| SCHEMBL16127955 | 0.70 | IDO1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |