Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 11/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231072 | 0.95 | MCHR1 (0.41) | DGAT1KCNH2MCHR1CNR2CNR1 | |
| SCHEMBL5234753 | 0.91 | DGAT1 (0.41) | DGAT1KCNH2MCHR1CNR2CNR1 | |
| SCHEMBL5236755 | 0.84 | MGLL (0.41) | DGAT1KCNH2MCHR1CNR2 | |
| SCHEMBL5237009 | 0.82 | DGAT1 (0.39) | DGAT1KCNH2MCHR1CNR2CNR1 | |
| SCHEMBL5239862 | 0.82 | SRD5A2 (0.39) | MCHR1CNR1 | |
| SCHEMBL5238842 | 0.81 | EGLN1 (0.43) | DGAT1MCHR1CNR1RET | |
| SCHEMBL5236952 | 0.81 | EGLN1 (0.46) | KCNH2MCHR1CNR2CNR1 | |
| SCHEMBL5237578 | 0.80 | KDM4E (0.43) | DGAT1KCNH2CNR2 | |
| SCHEMBL5233791 | 0.80 | PANK3 (0.41) | — | |
| SCHEMBL5233010 | 0.79 | MGLL (0.44) | DGAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |