SCHEMBL5239108

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5241422	0.86	CCR3 (0.46)	HTR1AEBPSIGMAR1RAB9A
	SCHEMBL14431859	0.84	CCR3 (0.54)	HTR1AKDM4EDRD2DRD3EBP
	SCHEMBL5240261	0.82	KCNH2 (0.53)	HRH3HTR1ADRD2DRD3SIGMAR1
	SCHEMBL5240351	0.82	HSD11B1 (0.43)	ALDH1A1EBPSIGMAR1
	SCHEMBL5239804	0.82	KCNA3 (0.60)	HTR1ADRD2DRD3EBPSIGMAR1
	SCHEMBL5240018	0.81	RAB9A (0.52)	DRD2DRD3EBPSIGMAR1RAB9A
	SCHEMBL5241342	0.80	DRD2 (0.44)	DRD2DRD3EBPSIGMAR1LMNA
	SCHEMBL5239484	0.80	RAB9A (0.52)	HTR1ACYP1A2DRD2DRD3SIGMAR1
	SCHEMBL5242817	0.80	HTR3A (0.45)	HTR3ADRD2DRD3EBPSIGMAR1
	SCHEMBL14431854	0.80	SIGMAR1 (0.51)	HTR1AKDM4EDRD2DRD3EBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.