Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254610 | 0.81 | SLC6A3 (0.44) | HTR2CMEN1KMT2AHTR2ASLC6A4 | |
| SCHEMBL3666428 | 0.81 | TAAR1 (0.44) | HTR2CNISCHHTR2AHTR2BNPC1 | |
| SCHEMBL2218295 | 0.80 | HTR2C (0.54) | HTR2CMEN1KMT2ANISCHHTR2A | |
| SCHEMBL240623 | 0.80 | ADCY5 (0.38) | HTR2CNISCHHTR2AHTR2BADRB1 | |
| SCHEMBL571789 | 0.79 | SLC18A3 (0.41) | NISCHMAOBDRD1 | |
| SCHEMBL1255265 | 0.77 | HTR1A (0.55) | HTR2CMEN1KMT2AHTR2AHTR2B | |
| SCHEMBL7289047 | 0.77 | MAOA (0.40) | HTR2CSLC6A4SLC6A3MAOB | |
| SCHEMBL8658279 | 0.75 | — | — | |
| SCHEMBL3169257 | 0.75 | HTR2C (0.46) | HTR2CMEN1KMT2AHTR2ASLC6A4 | |
| SCHEMBL6558765 | 0.73 | HTR2C (0.45) | HTR2CMEN1KMT2AHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865963-A2 | TRIAZADIBENZOAZULENE COMPOUNDS USEFUL FOR THE TREATMENT AND PREVENTION OF PAIN AND SCREENING METHODS THEREFOR | Acadia Pharmaceuticals Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006089286-A2 | TRIAZADIBENZOAZULENE COMPOUNDS USEFUL FOR THE TREATMENT AND PREVENTION OF PAIN AND SCREENING METHODS THEREFOR COMPOUNDS USEFUL FOR THE TREATMENT AND PREVENTION OF PAIN AND SCREENING METHODS THEREFOR | ACADIA PHARMACEUTICALS INC. (US) | 2006-08-24 | — | — | WO | claimed |