Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480819 | 1.00 | TRPV4 (0.52) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24400762 | 0.89 | KIF11 (0.44) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8577924 | 0.86 | KDM4E (0.41) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL18397439 | 0.84 | ALDH1A1 (0.43) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1420598 | 0.84 | KDM4E (0.40) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8946680 | 0.84 | KIF11 (0.41) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29858989 | 0.84 | ALDH1A1 (0.43) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL12464107 | 0.81 | KDM4E (0.38) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL15006214 | 0.81 | CYP19A1 (0.51) | TRPV4KIF11KDM4ECYP11B2CYP19A1 | |
| SCHEMBL18443352 | 0.80 | HSD11B1 (0.38) | TRPV4KIF11KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622712-A1 | SUBSTITUTED MACROCYCLIC AMINE MODULATORS OF OREXIN RECEPTOR 2 | Vertex Pharmaceuticals Incorporated (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112899-A1 | SUBSTITUTED MACROCYCLIC AMINE MODULATORS OF OREXIN RECEPTOR 2 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-117199519-A | Electrolyte, preparation method and application thereof, and lithium battery | 北京纳米能源与系统研究所 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023148215-A1 | 3,6-BIS(CYANOMETHYLIDENE)CYCLOHEXA-1,4-DIENE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONIC DEVICES | NOVALED GMBH (DE) | 2023-08-10 | — | — | WO | disclosed |
| EP-4223739-A1 | 3,6-BIS(CYANOMETHYLIDENE)CYCLOHEXA-1,4-DIENE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONIC DEVICES | Novaled GmbH (DE) | 2023-08-09 | — | — | EP | disclosed |
| EP-3657521-B1 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | NSK LTD (JP) | 2023-05-17 | — | — | EP | disclosed |
| CN-110998769-B | Dye-sensitized photoelectric conversion element | 日本精工株式会社 | 2022-07-01 | — | — | CN | disclosed |
| CN-114401963-A | Pesticidally active cyclic amine compounds | 先正达农作物保护股份公司 | 2022-04-26 | — | — | CN | disclosed |
| US-10784051-B2 | Dye-sensitized photoelectric conversion element | NSK LTD. (JP) | 2020-09-22 | — | — | US | disclosed |
| US-20200211787-A1 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | NSK LTD. (JP) | 2020-07-02 | — | — | US | disclosed |
| EP-1802632-B1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2011-07-13 | — | — | EP | disclosed |
| EP-1122242-B1 | CYANOPHENYL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2008-01-16 | — | — | EP | disclosed |
| EP-1802632-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2006-04-27 | — | — | US | disclosed |
| EP-0902026-B1 | Herbicidal 2-azinyl-6-aryloxypyr(mi)dines | BASF AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | disclosed |
| US-6673799-B1 | INHIBITS BINDING TO ANDROGEN RECEPTOR; ANTIANDROGEN | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1122242-A1 | CYANOPHENYL DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0902026-A1 | Herbicidal 2-azinyl-6-aryloxypyr (mi) dines | American Cyanamid Company (US) | 1999-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | TRPV4 2659/4885KIF11 2260/4885KDM4E 892/4885 |
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | TYMP, DPM1, TYMS | TRPV4 789/4885KIF11 3255/4885KDM4E 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.