Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480819 | 0.84 | TRPV4 (0.52) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL524167 | 0.84 | TRPV4 (0.52) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL8577924 | 0.82 | KDM4E (0.41) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL1420598 | 0.81 | KDM4E (0.40) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL29858989 | 0.81 | ALDH1A1 (0.43) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL18397439 | 0.81 | ALDH1A1 (0.43) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL18443350 | 0.80 | KDM4E (0.37) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL12464107 | 0.78 | KDM4E (0.38) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL18443352 | 0.77 | HSD11B1 (0.38) | KIF11KDM4EALDH1A1L3MBTL1CCR6 | |
| SCHEMBL1243269 | 0.76 | ALDH1A1 (0.46) | KIF11KDM4EALDH1A1L3MBTL1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135866-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (US) | 2012-05-31 | — | — | US | disclosed |
| US-8188292-B2 | Insecticidal N-substituted (heteroaryl)alkyl sulfilimines | DOW AGROSCIENCES, LLC (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100234398-A1 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILIMINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7754888-B2 | Insecticidal N-substituted (heteroaryl)alkyl sulfilimines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080280915-A1 | Insecticidal n-substituted (heteroaryl)alkyl sulfilimines | CORTEVA AGRISCIENCE LLC | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280915-A1 | Insecticidal n-substituted (heteroaryl)alkyl sulfilimines | AANAT, GNMT, STS | KIF11 4622/4885KDM4E 2799/4885ALDH1A1 2997/4885 |
| US-20120135866-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | KIF11 2881/4885KDM4E 2544/4885ALDH1A1 3063/4885 |
| US-20100234398-A1 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILIMINES | AANAT, GNMT, STS | KIF11 4622/4885KDM4E 2799/4885ALDH1A1 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.