SCHEMBL524258

SCHEMBL524258

CCC1(C(=O)O)c2ccccc2Oc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
P2RX4 Q99571 5/20 0.38
ALOX5 P09917 4/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
AKR1B1 P15121 1/20 0.37
P2RX1 P51575 1/20 0.36
THRB P10828 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PKM P14618 1/20 0.35
MAPT P10636 1/20 0.35
CHRM3 P20309 1/20 0.35
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromomethane SCHEMBL207850 0.97 KMT2A (0.37) KMT2AMEN1USP2P2RX4ALOX5
Propanol SCHEMBL27803554 0.92 KMT2A (0.36) KMT2AMEN1USP2P2RX4ALOX5
SCHEMBL523372 0.84 ALOX5 (0.39) KMT2AMEN1USP2P2RX4ALOX5
Bromomethane SCHEMBL208482 0.83 ALOX5 (0.36) KMT2AMEN1USP2P2RX4ALOX5
SCHEMBL10974812 0.82 AKR1B1 (0.43) KMT2AP2RX4ALOX5AKR1B1THRB
Bromide SCHEMBL27743791 0.82 ALOX5 (0.38) KMT2AMEN1USP2P2RX4ALOX5
SCHEMBL4221762 0.81 P2RX4 (0.41) KMT2AMEN1USP2P2RX4ALOX5
Bromomethane SCHEMBL15709779 0.80 ALOX5 (0.35) KMT2AMEN1USP2P2RX4ALOX5
SCHEMBL4743630 0.77 ALOX5 (0.35) P2RX4ALOX5AKR1B1THRBTDP1
SCHEMBL4747072 0.77 ALOX5 (0.35) P2RX4ALOX5AKR1B1P2RX1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152341-B2 ATOMIZER IN THE FORM OF AN INHALER FOR MEDICAL AEROSOL THERAPY BOEHRINGER INGELHEIM PHARMA (DE) 2025-04-02 EP disclosed
CN-110713489-B Heteroaryl SYK inhibitors 勃林格殷格翰国际有限公司 2022-05-31 CN disclosed
CN-110183440-B Heteroaryl SYK inhibitors 勃林格殷格翰国际有限公司 2022-04-22 CN disclosed
US-10947243-B2 Heteroaryl SYK inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-03-16 US disclosed
CN-110713489-A Heteroaryl SYK inhibitors 勃林格殷格翰国际有限公司 2020-01-21 CN disclosed
EP-3119765-B1 HETEROARYL SYK INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2019-07-17 EP disclosed
EP-3347353-B1 PYRAZOLYL-SUBSTITUTED HETEROARYLS AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INT (DE) 2019-07-17 EP disclosed
EP-3119772-B1 HETEROARYL SIK INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2019-05-22 EP disclosed
EP-3119766-B1 HETEROARYL SYK INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2019-05-22 EP disclosed
US-10155751-B2 Pyrazolyl-substituted heteroaryls and their use as medicaments BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-12-18 US disclosed
CN-102414177-A Compounds as bradykinin b1 antagonists BOEHRINGER INGELHEIM INT 2012-04-11 CN disclosed
US-20120028939-A1 SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-02-02 US disclosed
WO-2011092128-A1 SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-04 WO disclosed
US-20090155185-A1 MEDICAMENTS FOR INHALATION COMPRISING AN ANTICHOLINERGIC AND A BETAMIMETIC MEADE CHRISTOPHER JOHN MONTAGUE 2009-06-18 US disclosed
US-7405224-B2 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2008-07-29 US disclosed
CN-101043912-A Blister pack for an inhaler BOEHRINGER INGELHEIM INT (DE) 2007-09-26 CN disclosed
EP-1651224-A1 MEDICAMENTS FOR INHALATION COMPRISING ANTICHOLINERGICS AND A BETAMIMETIC Boehringer Ingelheim International GmbH (DE) 2006-05-03 EP disclosed
WO-2005013994-A1 MEDICAMENTS FOR INHALATION COMPRISING ANTICHOLINERGICS AND A BETAMIMETIC BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-17 WO disclosed
US-20050025718-A1 Medicaments for inhalation comprising an anticholinergic and a betamimetic BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-03 US disclosed
US-20030203928-A1 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH CO. KG (DE) 2003-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155185-A1 MEDICAMENTS FOR INHALATION COMPRISING AN ANTICHOLINERGIC AND A BETAMIMETIC ADRB2, CHRM3, ADRB1 KMT2A 3602/4885MEN1 2966/4885USP2 1187/4885
US-20120028939-A1 SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS NR4A3, NR0B1, NR4A1 KMT2A 4357/4885MEN1 2861/4885USP2 4652/4885
US-10155751-B2 Pyrazolyl-substituted heteroaryls and their use as medicaments HRH4, HRH3, HRH1 KMT2A 2183/4885MEN1 2244/4885USP2 4253/4885
US-10947243-B2 Heteroaryl SYK inhibitors SYK, BTK, CD40 KMT2A 733/4885MEN1 3116/4885USP2 3140/4885
US-20030203928-A1 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F11, NR3C2 KMT2A 1763/4885MEN1 345/4885USP2 3410/4885
US-20050025718-A1 Medicaments for inhalation comprising an anticholinergic and a betamimetic ADRB2, CHRM3, ADRB1 KMT2A 3602/4885MEN1 2966/4885USP2 1187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.