SCHEMBL523372

SCHEMBL523372

O=C(O)C1(CO)c2ccccc2Oc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.39
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
P2RX4 Q99571 3/20 0.36
CYP2C9 P11712 1/20 0.35
AKR1B1 P15121 1/20 0.35
ATM Q13315 1/20 0.34
P2RX1 P51575 1/20 0.34
P2RX3 P56373 1/20 0.34
LMNA P02545 1/20 0.34
HTR2A P28223 2/20 0.34
HRH1 P35367 2/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
KMT2A Q03164 1/20 0.33
APEX1 P27695 1/20 0.33
SLC6A1 P30531 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27743791 0.98 ALOX5 (0.38) ALOX5THRBTDP1P2RX4CYP2C9
Bromomethane SCHEMBL208482 0.95 ALOX5 (0.36) ALOX5THRBTDP1P2RX4CYP2C9
SCHEMBL10974812 0.84 AKR1B1 (0.43) ALOX5THRBTDP1P2RX4CYP2C9
SCHEMBL524258 0.84 KMT2A (0.39) ALOX5THRBTDP1P2RX4CYP2C9
Bromomethane SCHEMBL15709779 0.82 ALOX5 (0.35) ALOX5THRBTDP1P2RX4CYP2C9
Bromomethane SCHEMBL207850 0.81 KMT2A (0.37) ALOX5THRBTDP1P2RX4AKR1B1
Propanol SCHEMBL27803554 0.80 KMT2A (0.36) ALOX5THRBTDP1P2RX4AKR1B1
SCHEMBL27681375 0.80 CHRM3 (0.32) LMNAHRH1MEN1KMT2ACHRM2
SCHEMBL5285126 0.79 THRB (0.55) THRBTDP1KMT2AAPEX1
SCHEMBL4743630 0.78 ALOX5 (0.35) ALOX5THRBTDP1P2RX4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152341-B2 ATOMIZER IN THE FORM OF AN INHALER FOR MEDICAL AEROSOL THERAPY BOEHRINGER INGELHEIM PHARMA (DE) 2025-04-02 EP disclosed
US-12209094-B2 CCR2 receptor antagonists and uses thereof CENTREXION THERAPEUTICS CORPORATION (US) 2025-01-28 US disclosed
US-20240109909-A1 CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2024-04-04 US disclosed
US-11731981-B2 CCR2 receptor antagonists and uses thereof CENTREXION THERAPEUTICS CORPORATION (US) 2023-08-22 US disclosed
CN-110713489-B Heteroaryl SYK inhibitors 勃林格殷格翰国际有限公司 2022-05-31 CN disclosed
CN-110183440-B Heteroaryl SYK inhibitors 勃林格殷格翰国际有限公司 2022-04-22 CN disclosed
US-10947243-B2 Heteroaryl SYK inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-03-16 US disclosed
EP-2026761-B1 INHALANT PROPELLANT-FREE AEROSOL FORMULATION BOEHRINGER INGELHEIM INT (DE) 2020-04-15 EP disclosed
EP-3347353-B1 PYRAZOLYL-SUBSTITUTED HETEROARYLS AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INT (DE) 2019-07-17 EP disclosed
EP-3119765-B1 HETEROARYL SYK INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2019-07-17 EP disclosed
EP-2011536-A1 Inhaler Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2009-01-07 EP disclosed
US-7405224-B2 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2008-07-29 US disclosed
CN-101166723-A New compound for the treatinginflammatory disease BOEHRINGER INGELHEIM PHARMA (DE) 2008-04-23 CN disclosed
US-20070282276-A1 PROCESS AND DEVICE FOR DOSING PHARMACEUTICAL AGENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-12-06 US disclosed
US-20060134007-A1 Blister for inhalers BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-22 US disclosed
EP-1651224-A1 MEDICAMENTS FOR INHALATION COMPRISING ANTICHOLINERGICS AND A BETAMIMETIC Boehringer Ingelheim International GmbH (DE) 2006-05-03 EP disclosed
WO-2005013994-A1 MEDICAMENTS FOR INHALATION COMPRISING ANTICHOLINERGICS AND A BETAMIMETIC BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-17 WO disclosed
US-20050025718-A1 Medicaments for inhalation comprising an anticholinergic and a betamimetic BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-03 US disclosed
US-20030203928-A1 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH CO. KG (DE) 2003-10-30 US disclosed
CN-1309655-A Cyclic compounds useful in treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions and preparation process MERCK PATENT GMBH (DE) 2001-08-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731981-B2 CCR2 receptor antagonists and uses thereof CCR2, CCRL2, CCR1 ALOX5 1906/4885THRB 1526/4885TDP1 4831/4885
US-10947243-B2 Heteroaryl SYK inhibitors SYK, BTK, CD40 ALOX5 1323/4885THRB 1837/4885TDP1 2364/4885
US-20240109909-A1 CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF CCR2, CCRL2, CCR1 ALOX5 1906/4885THRB 1526/4885TDP1 4831/4885
US-20030203928-A1 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F11, NR3C2 ALOX5 2833/4885THRB 3210/4885TDP1 2982/4885
US-12209094-B2 CCR2 receptor antagonists and uses thereof CCR2, CCRL2, CCR1 ALOX5 1906/4885THRB 1526/4885TDP1 4831/4885
US-20050025718-A1 Medicaments for inhalation comprising an anticholinergic and a betamimetic ADRB2, CHRM3, ADRB1 ALOX5 1020/4885THRB 804/4885TDP1 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.