Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246777 | 0.79 | TSPO (0.49) | ALDH1A1KDM4ETSHRPOLBKMT2A | |
| SCHEMBL4841869 | 0.77 | MEN1 (0.52) | ALDH1A1KDM4ETSHRPOLBHTT | |
| SCHEMBL5209687 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRPOLBHTT | |
| SCHEMBL30465852 | 0.74 | APLNR (0.51) | ALDH1A1KDM4ETSHRPOLBHTT | |
| SCHEMBL341820 | 0.73 | TDP1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL7576003 | 0.70 | TSPO (0.71) | TSPO | |
| SCHEMBL6582986 | 0.70 | TDP1 (0.48) | ALDH1A1KDM4ETSHRPOLBHTT | |
| SCHEMBL1097902 | 0.69 | HSD17B10 (0.75) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL30831943 | 0.69 | HSD17B10 (0.75) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL3651761 | 0.69 | TDP1 (0.70) | TSHRPOLBHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |