Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247428 | 0.97 | HPGD (0.44) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3113751 | 0.92 | HPGD (0.41) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5246507 | 0.92 | ALDH1A1 (0.34) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5247123 | 0.88 | NPC1 (0.45) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3104271 | 0.88 | CYP1A2 (0.38) | HPGDNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5246279 | 0.88 | RAB9A (0.40) | HPGDNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5245108 | 0.88 | NPC1 (0.37) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3106801 | 0.88 | HDAC4 (0.35) | HPGDNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3118432 | 0.87 | L3MBTL1 (0.43) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3112810 | 0.87 | MLYCD (0.36) | HPGDNPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |