Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CSF1R | P07333 | 6/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247652 | 0.87 | MAPT (0.47) | MAPTCSF1REGFRLMNAKMT2A | |
| SCHEMBL5244192 | 0.86 | MAPT (0.43) | MAPTCSF1REGFRLMNAKMT2A | |
| SCHEMBL17815794 | 0.85 | MAPT (0.43) | MAPTCSF1RLMNAKMT2AMEN1 | |
| SCHEMBL2019674 | 0.84 | CA1 (0.43) | MAPTCSF1REGFRLMNAKMT2A | |
| SCHEMBL17815790 | 0.82 | PRMT1 (0.43) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL9124886 | 0.80 | HTT (0.64) | MAPTCSF1REGFRLMNAKMT2A | |
| SCHEMBL8078419 | 0.80 | LMNA (0.40) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL12459324 | 0.80 | LMNA (0.73) | MAPTCSF1RLMNAKMT2AMEN1 | |
| SCHEMBL14797801 | 0.76 | LMNA (0.54) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL5244332 | 0.74 | EGFR (0.53) | MAPTCSF1REGFRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848506-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | Attenuon, LLC (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006089298-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | ATTENUON, LLC (US) | 2006-08-24 | — | — | WO | disclosed |