Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244192 | 0.88 | MAPT (0.43) | MAPTMEN1KMT2AEGFRCSF1R | |
| SCHEMBL5244451 | 0.87 | MAPT (0.58) | MAPTMEN1KMT2AEGFRCSF1R | |
| SCHEMBL2019674 | 0.85 | CA1 (0.43) | MAPTMEN1KMT2AEGFRCSF1R | |
| SCHEMBL17815794 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2ACSF1RLMNA | |
| SCHEMBL17815790 | 0.83 | PRMT1 (0.43) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL8078419 | 0.79 | LMNA (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL5243561 | 0.75 | EGFR (0.46) | EGFRCSF1RALDH1A1PDGFRBKDR | |
| SCHEMBL9124007 | 0.72 | ALDH1A1 (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL304909 | 0.71 | CA1 (0.49) | MAPTKMT2ALMNAHTTNPC1 | |
| SCHEMBL2542634 | 0.70 | LMNA (0.43) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848506-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | Attenuon, LLC (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006089298-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | ATTENUON, LLC (US) | 2006-08-24 | — | — | WO | disclosed |