Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124007 | 0.81 | ALDH1A1 (0.40) | LMNACA1CA2CA7CA13 | |
| SCHEMBL304909 | 0.80 | CA1 (0.49) | LMNACA1CA2CA7CA13 | |
| SCHEMBL14805351 | 0.80 | LMNA (0.41) | LMNAHTTALDH1A1MAPTMEN1 | |
| SCHEMBL2542634 | 0.80 | LMNA (0.43) | LMNACA1CA2CA7CA13 | |
| SCHEMBL5244451 | 0.80 | MAPT (0.58) | LMNAHTTALDH1A1MAPTMEN1 | |
| SCHEMBL5247652 | 0.79 | MAPT (0.47) | LMNACA1CA2CA7CA13 | |
| SCHEMBL9123271 | 0.78 | LMNA (0.49) | LMNACA1CA2CA7CA13 | |
| SCHEMBL5244192 | 0.78 | MAPT (0.43) | LMNACA1CA2CA7CA13 | |
| SCHEMBL12459324 | 0.77 | LMNA (0.73) | LMNAHTTALDH1A1MAPTMEN1 | |
| SCHEMBL13866827 | 0.76 | ALDH1A1 (0.40) | LMNACA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535394-A | Carbon nitrogen bond diazole energetic compound with polynitro modification or usable salt thereof and preparation method thereof | 北京理工大学 | 2023-08-04 | — | — | CN | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-6025489-A | Tricyclic pteridinones and a process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0429149-B1 | Tricyclic pteridinones and a process for their preparation | BERLEX LAB (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5854419-A | Tricyclic pteridinones and a process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |
| US-5668136-A | ANTIARTERIOSCLEROTIC AGENT, CHOLESTEROL O-ACYLTRANSFERASE INHIBITOR | EISAI CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| US-5602252-A | Tricyclic pteridinones and a process for their preparation | BERLEX LABORATORIES, INC. | 1997-02-11 | — | — | US | disclosed |
| CN-1122331-A | Benzene, pyridine and pyrimidine derivative | EISAI CO LTD (JP) | 1996-05-15 | — | — | CN | disclosed |
| EP-0477778-B1 | Benzene, pyridine and pyrimidine derivative | EISAI CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5442060-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0615970-A1 | Benzene, pyridine and pyrimidine derivative | Eisai Co., Ltd. (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0591830-A1 | Carboxamide and urea derivatives having ACAT-inhibiting activityM | Mitsubishi Chemical Corporation (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |
| CN-1060466-A | Derivatives of Benzene, Pyridine and Pyrimidine | EISAI CO LTD (JP) | 1992-04-22 | — | — | CN | disclosed |
| EP-0477778-A2 | Benzene, pyridine and pyrimidine derivative | Eisai Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0429149-A1 | Tricyclic pteridinones and a process for their preparation | BERLEX LABORATORIES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |