Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250048 | 0.88 | EPHX2 (0.46) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5245240 | 0.87 | HPGD (0.45) | MAOACCR1MEN1KMT2AHPGD | |
| SCHEMBL5244539 | 0.86 | SMO (0.44) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5248134 | 0.85 | P2RX3 (0.42) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5248045 | 0.85 | GRM5 (0.43) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5247431 | 0.85 | RIPK1 (0.44) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5245587 | 0.84 | RAB9A (0.49) | MAOACCR1MEN1KMT2ALMNA | |
| SCHEMBL5245586 | 0.84 | CCR1 (0.46) | CCR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5244893 | 0.84 | MAPK14 (0.48) | MAOACCR1EPHX2HDAC1 | |
| Trifluoroacetic Acid SCHEMBL5246743 | 0.83 | MAPK14 (0.44) | MEN1KMT2AHPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |