Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246308 | 0.92 | RAB9A (0.42) | HPGDRAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL5250048 | 0.90 | EPHX2 (0.46) | HPGDMIFRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5244893 | 0.88 | MAPK14 (0.48) | RECQLMAOACCR1NAMPT | |
| SCHEMBL5247721 | 0.87 | CCR1 (0.40) | HPGDMIFRAB9ASMN1; SMN2TP53 | |
| SCHEMBL5248045 | 0.87 | GRM5 (0.43) | HPGDMIFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5244571 | 0.87 | MAOA (0.41) | HPGDMIFSMN1; SMN2TP53POLB | |
| SCHEMBL5250501 | 0.86 | KDM4E (0.52) | HPGDRAB9ASMN1; SMN2HTT | |
| Trifluoroacetic Acid SCHEMBL5249602 | 0.86 | LMNA (0.43) | HPGDSMN1; SMN2HTTCYP3A4MEN1 | |
| SCHEMBL5250025 | 0.86 | LOX (0.40) | HPGDMIFCYP2D6CYP2C19MEN1 | |
| SCHEMBL5244539 | 0.86 | SMO (0.44) | HPGDMIFSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |