Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5243967 | 0.92 | RAB9A (0.44) | NPC1RAB9APTGER1KMT2AMEN1 | |
| SCHEMBL5250048 | 0.90 | EPHX2 (0.46) | MAPK14LMNARAB9AKMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5249602 | 0.89 | LMNA (0.43) | MAPK14LMNAPTGER1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5250686 | 0.88 | LMNA (0.46) | LMNAPOLBPTGER1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5244195 | 0.87 | SCN9A (0.36) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5244539 | 0.86 | SMO (0.44) | LMNAKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL5244893 | 0.86 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL5248134 | 0.86 | P2RX3 (0.42) | LMNAKMT2AMEN1HPGDMIF | |
| SCHEMBL5248045 | 0.85 | GRM5 (0.43) | LMNAKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL5245240 | 0.85 | HPGD (0.45) | POLBRAB9AKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |