Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 3/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250068 | 0.91 | BRD4 (0.36) | DDTROCK2MIFPSEN1PSEN2 | |
| SCHEMBL5248109 | 0.89 | EGLN1 (0.38) | DDTLOXL2ROCK2MIFPSEN1 | |
| SCHEMBL5246041 | 0.89 | MIF (0.45) | DDTMIFPSEN1PSEN2APH1B | |
| SCHEMBL5246077 | 0.88 | MMP13 (0.37) | DDTMIFPSEN1PSEN2APH1B | |
| SCHEMBL5246799 | 0.88 | PSEN1 (0.41) | DDTMIFPSEN1PSEN2APH1B | |
| SCHEMBL5246995 | 0.88 | DDT (0.41) | DDTROCK2MIFPSEN1PSEN2 | |
| SCHEMBL5247824 | 0.87 | MMP13 (0.39) | DDTROCK2MIFPSEN1PSEN2 | |
| SCHEMBL3111267 | 0.86 | GLS (0.43) | DDTROCK2MIFPSEN1PSEN2 | |
| SCHEMBL5244109 | 0.86 | MIF (0.47) | MIF | |
| SCHEMBL5247166 | 0.86 | EPHX2 (0.41) | DDTMIFEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |