Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250048 | 0.94 | EPHX2 (0.46) | LMNAMAPK14SMN1; SMN2EPHX2MEN1 | |
| Trifluoroacetic Acid SCHEMBL5250686 | 0.92 | LMNA (0.46) | LMNAMMP13HTTSMN1; SMN2MAPK1 | |
| SCHEMBL5244893 | 0.92 | MAPK14 (0.48) | MAPK14EPHX2CCR1IDH1 | |
| SCHEMBL5244539 | 0.90 | SMO (0.44) | LMNASMN1; SMN2EPHX2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5246743 | 0.89 | MAPK14 (0.44) | LMNAMAPK14SMN1; SMN2PTGER1MEN1 | |
| SCHEMBL5245587 | 0.89 | RAB9A (0.49) | LMNAEPHX2MEN1KMT2ACCR1 | |
| SCHEMBL5244146 | 0.88 | CCR1 (0.42) | LMNAMAPK14SMN1; SMN2PTGER1EPHX2 | |
| SCHEMBL5248303 | 0.88 | SMN1; SMN2 (0.47) | MAPK14SMN1; SMN2EPHX2MEN1KMT2A | |
| SCHEMBL5247431 | 0.88 | RIPK1 (0.44) | LMNAMAPK14SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL5249371 | 0.87 | CCR1 (0.49) | LMNACYP3A4MAPK14EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |