SCHEMBL5245265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5246328	0.92	CES2 (0.40)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL5358419	0.89	MEN1 (0.38)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL5350330	0.89	MEN1 (0.38)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL5251554	0.81	ALDH1A1 (0.50)	HDAC1HDAC2MEN1KMT2AALDH1A1
	SCHEMBL18660231	0.81	CES2 (0.50)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL7713583	0.81	CES2 (0.50)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL22922164	0.79	CES2 (0.48)	CES2CYP2C19EPHX2MEN1KMT2A
	SCHEMBL26633456	0.78	MEN1 (0.39)	CES2HDAC1HDAC2MEN1KMT2A
	SCHEMBL10001230	0.78	CES2 (0.46)	CES2CYP2C19HDAC1HDAC2EPHX2
	SCHEMBL27297810	0.78	CES2 (0.41)	CES2CYP2C19HDAC1HDAC2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.