Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | DDT | P30046 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246579 | 0.92 | WDR5 (0.38) | P2RX3P2RX2WDR5MAPTAPP | |
| SCHEMBL5244591 | 0.86 | DDT (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5248109 | 0.85 | EGLN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5246041 | 0.85 | MIF (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3102931 | 0.85 | TP53 (0.39) | MAPT | |
| SCHEMBL3104911 | 0.85 | S1PR1 (0.41) | — | |
| SCHEMBL5246077 | 0.85 | MMP13 (0.37) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244708 | 0.84 | DDT (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5247166 | 0.84 | EPHX2 (0.41) | DDT | |
| SCHEMBL5244109 | 0.84 | MIF (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |