Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245389 | 0.92 | P2RX3 (0.37) | WDR5MAPTAPPP2RX3P2RX2 | |
| SCHEMBL5246767 | 0.85 | MIF (0.47) | BRD4GLSMIF | |
| SCHEMBL5244706 | 0.85 | ROCK2 (0.40) | BRD4MIF | |
| SCHEMBL5245552 | 0.85 | PDE10A (0.36) | APPBRD4BRD2BRD3BRDT | |
| SCHEMBL5244462 | 0.85 | MAPT (0.40) | MAPTBRD4MIF | |
| SCHEMBL5250068 | 0.84 | BRD4 (0.36) | BRD4MIF | |
| SCHEMBL5247626 | 0.84 | MIF (0.48) | MAPTMIF | |
| SCHEMBL5248700 | 0.84 | ROCK2 (0.41) | MAPTBRD4MIF | |
| SCHEMBL3113676 | 0.84 | ACKR3 (0.41) | BRD4GLS | |
| SCHEMBL5248284 | 0.84 | NPSR1 (0.37) | APPBRD4GLSMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |