Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249116 | 0.91 | NPC1 (0.50) | HPGDRAB9ATP53MAPTALDH1A1 | |
| SCHEMBL5249036 | 0.85 | KDM4E (0.54) | HPGDRAB9AMAPTALDH1A1PKM | |
| SCHEMBL5244694 | 0.85 | HPGD (0.48) | HPGDRAB9AMIFMAPTALDH1A1 | |
| SCHEMBL5246544 | 0.84 | HPGD (0.38) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5247706 | 0.84 | HPGD (0.39) | HPGDTP53MAPTALDH1A1MEN1 | |
| SCHEMBL5246905 | 0.83 | GRM5 (0.42) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5247742 | 0.83 | HPGD (0.39) | HPGDRAB9ATP53ALDH1A1MEN1 | |
| SCHEMBL5244587 | 0.83 | L3MBTL1 (0.45) | HPGDRAB9AMAPTALDH1A1POLB | |
| SCHEMBL3112834 | 0.82 | HPGD (0.43) | HPGDRAB9ATP53MAPTALDH1A1 | |
| SCHEMBL5247403 | 0.82 | LMNA (0.39) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |