Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245667 | 0.83 | HPGD (0.56) | HPGDALDH1A1POLBMAPTRAB9A | |
| SCHEMBL5249116 | 0.81 | NPC1 (0.50) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3109368 | 0.79 | ALDH1A1 (0.43) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3109364 | 0.79 | ALDH1A1 (0.43) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3114145 | 0.78 | CYP1A2 (0.42) | HPGDATMALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5246648 | 0.78 | NAMPT (0.39) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5249036 | 0.77 | KDM4E (0.54) | HPGDALDH1A1POLBMAPTRAB9A | |
| SCHEMBL5244694 | 0.77 | HPGD (0.48) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5247706 | 0.77 | HPGD (0.39) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3112551 | 0.77 | XDH (0.45) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |