Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245667 | 0.84 | HPGD (0.56) | HPGDALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL5246905 | 0.83 | GRM5 (0.42) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5244404 | 0.83 | P2RX3 (0.45) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5244456 | 0.82 | LMNA (0.57) | ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL5244694 | 0.82 | HPGD (0.48) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3106881 | 0.82 | ROCK2 (0.42) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3112834 | 0.82 | HPGD (0.43) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5249308 | 0.81 | RIPK1 (0.46) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5246544 | 0.80 | HPGD (0.38) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3112551 | 0.80 | XDH (0.45) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |