Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DDT | P30046 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246709 | 0.92 | ROCK2 (0.42) | ROCK2ROCK1DDTMMP13BRD4 | |
| SCHEMBL5246767 | 0.91 | MIF (0.47) | DDTBRD4PSEN1PSEN2APH1B | |
| SCHEMBL5250510 | 0.91 | DDT (0.41) | ROCK2ROCK1DDTMMP13THRB | |
| SCHEMBL5246030 | 0.91 | LMNA (0.42) | ROCK2ROCK1DDTBRD4PSEN1 | |
| SCHEMBL5244638 | 0.90 | LMNA (0.39) | ROCK2ROCK1DDTMMP13BRD4 | |
| SCHEMBL5244747 | 0.90 | BRD4 (0.47) | ROCK2ROCK1DDTMMP13BRD4 | |
| SCHEMBL5248346 | 0.90 | ROCK2 (0.45) | ROCK2ROCK1DDTBRD4PSEN1 | |
| SCHEMBL5247657 | 0.90 | LMNA (0.46) | DDTBRD4MIF | |
| SCHEMBL5248515 | 0.89 | DDT (0.39) | ROCK2ROCK1DDTBRD4PSEN1 | |
| SCHEMBL5244424 | 0.89 | DDT (0.52) | ROCK2ROCK1DDTMMP13PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |