Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DDT | P30046 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244638 | 0.94 | LMNA (0.39) | LMNAWDR5BRD4DDT | |
| SCHEMBL5245570 | 0.91 | LMNA (0.42) | LMNAMAOBEPHX2WDR5HDAC4 | |
| SCHEMBL5246245 | 0.90 | ROCK2 (0.41) | BRD4DDTMIF | |
| SCHEMBL5245935 | 0.90 | ROCK2 (0.41) | BRD4DDTMIF | |
| SCHEMBL5244462 | 0.90 | MAPT (0.40) | BRD4MIF | |
| SCHEMBL5244706 | 0.89 | ROCK2 (0.40) | BRD4DDTMIF | |
| SCHEMBL5246767 | 0.89 | MIF (0.47) | LMNAEPHX2BRD4DDTMIF | |
| SCHEMBL5246709 | 0.88 | ROCK2 (0.42) | LMNABRD4DDTMIF | |
| SCHEMBL5247395 | 0.88 | DDT (0.43) | EPHX2PPARGHDAC1DDTMIF | |
| SCHEMBL5247966 | 0.88 | EPHX2 (0.43) | LMNAEPHX2HDAC8HDAC6MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |