Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248174 | 0.89 | POLB (0.48) | CCR1THRBMAPTLMNA | |
| SCHEMBL5244366 | 0.89 | CCR1 (0.45) | CCR1ROCK2THRBMMP13GAA | |
| SCHEMBL5246022 | 0.89 | CCR1 (0.43) | CCR1ROCK2MAPTLMNA | |
| SCHEMBL5244694 | 0.89 | HPGD (0.48) | ROCK2HDAC1MAPTLMNA | |
| SCHEMBL5244269 | 0.88 | CNR1 (0.49) | CCR1HDAC1LMNA | |
| SCHEMBL5244114 | 0.88 | CCR1 (0.43) | CCR1HDAC1GAAMAPTLMNA | |
| SCHEMBL5248119 | 0.88 | ALDH1A1 (0.43) | CCR1ROCK2MAPTLMNA | |
| SCHEMBL5248724 | 0.88 | PRKACA (0.50) | ROCK2MMP13GAAMAPTLMNA | |
| SCHEMBL5246674 | 0.88 | ROCK2 (0.53) | CCR1ROCK2THRBMAPTLMNA | |
| SCHEMBL5244318 | 0.87 | CCR1 (0.59) | CCR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |