Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246022 | 0.89 | CCR1 (0.43) | LMNAMAPTCCR1HPGDMEN1 | |
| SCHEMBL5244366 | 0.89 | CCR1 (0.45) | LMNATP53MAPTCCR1MEN1 | |
| SCHEMBL5246361 | 0.89 | CCR1 (0.49) | LMNAMAPTCCR1THRB | |
| SCHEMBL5244694 | 0.89 | HPGD (0.48) | LMNAMAPTHPGDMEN1KMT2A | |
| SCHEMBL5248119 | 0.88 | ALDH1A1 (0.43) | POLBLMNAMAPTCCR1HPGD | |
| SCHEMBL5248724 | 0.88 | PRKACA (0.50) | POLBLMNATP53MAPTHPGD | |
| SCHEMBL5246674 | 0.88 | ROCK2 (0.53) | POLBLMNATP53MAPTCCR1 | |
| SCHEMBL5244318 | 0.87 | CCR1 (0.59) | CCR1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5248441 | 0.85 | ROCK2 (0.43) | POLBTP53MAPTCCR1SMN1; SMN2 | |
| SCHEMBL5249263 | 0.85 | LMNA (0.45) | LMNACCR1HPGDIDO1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |