Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249308 | 0.92 | RIPK1 (0.46) | CCR1BRD4LMNAMAPTROCK2 | |
| SCHEMBL5248728 | 0.91 | ABCB1 (0.47) | BRD4LMNAMAPTTP53NAMPT | |
| SCHEMBL3113720 | 0.91 | CCR1 (0.43) | CCR1BRD4LMNAMAPTROCK2 | |
| SCHEMBL5249263 | 0.91 | LMNA (0.45) | CCR1LMNAROCK2ALDH1A1 | |
| SCHEMBL3108441 | 0.90 | CCR1 (0.47) | CCR1BRD4LMNAMAPTROCK2 | |
| SCHEMBL5246361 | 0.89 | CCR1 (0.49) | CCR1LMNAMAPTROCK2THRB | |
| SCHEMBL5246022 | 0.89 | CCR1 (0.43) | CCR1LMNAMAPTROCK2MEN1 | |
| SCHEMBL5248174 | 0.89 | POLB (0.48) | CCR1LMNAMAPTTP53THRB | |
| SCHEMBL5244456 | 0.89 | LMNA (0.57) | LMNAMAPTALDH1A1 | |
| SCHEMBL5244694 | 0.89 | HPGD (0.48) | LMNAMAPTROCK2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |