Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112551 | 0.82 | XDH (0.45) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3114145 | 0.80 | CYP1A2 (0.42) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3112309 | 0.80 | GAA (0.50) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3112318 | 0.80 | GAA (0.50) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3109368 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3109364 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3112834 | 0.79 | HPGD (0.43) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3113746 | 0.79 | RIPK1 (0.41) | NAMPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL5246149 | 0.78 | RAB9A (0.43) | NAMPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL3114784 | 0.78 | RIPK1 (0.39) | ALDH1A1HPGDCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |