Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246728 | 0.92 | GLS (0.34) | L3MBTL1MIFPDE4APDE4BPDE4C | |
| SCHEMBL5247626 | 0.86 | MIF (0.48) | MIFALDH1A1GAAKMT2AMAPT | |
| SCHEMBL5246911 | 0.85 | NPC1 (0.45) | BRD4MIFALDH1A1GAAPOLB | |
| SCHEMBL5247572 | 0.82 | TAS1R3 (0.36) | BRD4 | |
| SCHEMBL5244465 | 0.81 | KDM4E (0.47) | MIFALDH1A1POLBMAPT | |
| SCHEMBL5246767 | 0.81 | MIF (0.47) | BRD4L3MBTL1MIFALDH1A1GAA | |
| SCHEMBL5245552 | 0.81 | PDE10A (0.36) | BRD4MIFGLS | |
| SCHEMBL5250068 | 0.80 | BRD4 (0.36) | BRD4MIF | |
| SCHEMBL5248700 | 0.80 | ROCK2 (0.41) | BRD4MIFPDE4DALDH1A1KMT2A | |
| SCHEMBL5246426 | 0.80 | BRD4 (0.41) | BRD4MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |