Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244465 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL5244109 | 0.87 | MIF (0.47) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL5244507 | 0.83 | BRD4 (0.40) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL5244708 | 0.83 | DDT (0.35) | MIF | |
| SCHEMBL5246041 | 0.83 | MIF (0.45) | ALDH1A1LMNAMIF | |
| SCHEMBL5245389 | 0.82 | P2RX3 (0.37) | MAPT | |
| SCHEMBL5244591 | 0.82 | DDT (0.34) | LMNAMIF | |
| SCHEMBL5246728 | 0.81 | GLS (0.34) | ALDH1A1MAPTPOLBMIF | |
| SCHEMBL5244350 | 0.81 | ROCK2 (0.38) | ALDH1A1LMNAKLKB1MIF | |
| SCHEMBL5245310 | 0.81 | DRD2 (0.38) | MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |