Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453628 | 0.84 | HSD17B2 (0.42) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL6461326 | 0.83 | SLC1A3 (0.41) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL4364840 | 0.79 | ALDH1A1 (0.49) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL29065806 | 0.79 | ALDH1A1 (0.49) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL28814771 | 0.79 | ALDH1A1 (0.49) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL25527441 | 0.78 | CES2 (0.36) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL5911245 | 0.77 | SLC6A2 (0.38) | ALOX5CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL658090 | 0.77 | CES2 (0.46) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| Ethane SCHEMBL4831611 | 0.76 | CES2 (0.46) | FFAR1ALOX5RAB9AALDH1A1NPC1 | |
| SCHEMBL24328836 | 0.75 | ALOX5 (0.45) | ALOX5RAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924386-B2 | Enantioselective reformatsky process for preparing optically active alcohols, amines and derivatives thereof | Consortium für elektrochemische Industrie GmbH (DE) | 2005-08-02 | — | — | US | disclosed |
| US-20040096211-A1 | Enantioselective reformatsky process for preparing optically active alcohols, amines and derivatives thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-05-20 | — | — | US | disclosed |