Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451012 | 0.84 | FFAR1 (0.41) | MMP12ALOX5ALDH1A1RAB9ANPC1 | |
| SCHEMBL25527441 | 0.82 | CES2 (0.36) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL6461326 | 0.80 | SLC1A3 (0.41) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3895136 | 0.79 | ALOX5 (0.40) | HSD17B2ALOX5ALDH1A1RAB9ANPC1 | |
| SCHEMBL3936766 | 0.79 | ALOX5 (0.40) | HSD17B2ALOX5ALDH1A1RAB9ANPC1 | |
| SCHEMBL3936768 | 0.79 | ALOX5 (0.40) | HSD17B2ALOX5ALDH1A1RAB9ANPC1 | |
| SCHEMBL5848158 | 0.79 | ALOX5 (0.40) | HSD17B2ALOX5ALDH1A1RAB9ANPC1 | |
| SCHEMBL3898505 | 0.78 | CACNA2D1 (0.47) | HSD17B2ALOX5POLBLMNATP53 | |
| SCHEMBL3898507 | 0.78 | CACNA2D1 (0.47) | HSD17B2ALOX5POLBLMNATP53 | |
| SCHEMBL5915026 | 0.77 | LMNA (0.39) | HSD17B2ALOX5CES2CES1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924386-B2 | Enantioselective reformatsky process for preparing optically active alcohols, amines and derivatives thereof | Consortium für elektrochemische Industrie GmbH (DE) | 2005-08-02 | — | — | US | disclosed |
| US-20040096211-A1 | Enantioselective reformatsky process for preparing optically active alcohols, amines and derivatives thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-05-20 | — | — | US | disclosed |