Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5245953 | 0.90 | MAPT (0.30) | MAPTSMN1; SMN2 | |
| SCHEMBL5248904 | 0.84 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2BRD4RAB9ADRD2 | |
| SCHEMBL5244426 | 0.79 | DRD2 (0.37) | BRD4RAB9ADRD2DRD3 | |
| SCHEMBL5246426 | 0.78 | BRD4 (0.41) | BRD4DRD2DRD3 | |
| SCHEMBL5246245 | 0.77 | ROCK2 (0.41) | BRD4 | |
| SCHEMBL5247137 | 0.77 | SMPD1 (0.40) | MAPTSMN1; SMN2BRD4 | |
| SCHEMBL5246401 | 0.77 | BRD4 (0.41) | MAPTSMN1; SMN2BRD4RAB9A | |
| SCHEMBL5250335 | 0.76 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2DRD2DRD3 | |
| SCHEMBL5248700 | 0.76 | ROCK2 (0.41) | MAPTBRD4 | |
| SCHEMBL5244299 | 0.76 | BRD4 (0.35) | BRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |