Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250048 | 0.93 | EPHX2 (0.46) | SMN1; SMN2EPHX2MAPK14MEN1KMT2A | |
| SCHEMBL5247606 | 0.92 | MAPK14 (0.54) | SMN1; SMN2MAPK14NAMPTABCB1 | |
| SCHEMBL5244539 | 0.91 | SMO (0.44) | SMN1; SMN2PTGER4EPHX2L3MBTL1MEN1 | |
| SCHEMBL5244893 | 0.91 | MAPK14 (0.48) | PTGER4EPHX2MAPK14NAMPTPPARG | |
| SCHEMBL5245587 | 0.89 | RAB9A (0.49) | EPHX2NR1H4L3MBTL1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5249602 | 0.88 | LMNA (0.43) | SMN1; SMN2EPHX2MAPK14ABCB1MEN1 | |
| SCHEMBL5249014 | 0.87 | CCR1 (0.45) | SMN1; SMN2PTGER4EPHX2NR1H4MAPK14 | |
| SCHEMBL5247431 | 0.87 | RIPK1 (0.44) | SMN1; SMN2EPHX2MAPK14NAMPTMEN1 | |
| SCHEMBL5248465 | 0.86 | CCR1 (0.46) | SMN1; SMN2PPARGABCB1MEN1KMT2A | |
| SCHEMBL5245586 | 0.86 | CCR1 (0.46) | PTGER4EPHX2MAPK14NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |