Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116264 | 0.90 | MEN1 (0.58) | MEN1KMT2AMAPTTDP1HPGD | |
| SCHEMBL13158518 | 0.87 | MAPT (0.61) | MEN1KMT2AMAPTTDP1HPGD | |
| SCHEMBL5245295 | 0.85 | LMNA (0.44) | MAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5244269 | 0.85 | CNR1 (0.49) | — | |
| SCHEMBL5244456 | 0.84 | LMNA (0.57) | MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL5244694 | 0.84 | HPGD (0.48) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3109229 | 0.83 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL5249308 | 0.83 | RIPK1 (0.46) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL5246092 | 0.83 | EPHX2 (0.53) | MEN1KMT2ANPC1 | |
| SCHEMBL5244114 | 0.83 | CCR1 (0.43) | MEN1KMT2AMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |