Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249308 | 0.91 | RIPK1 (0.46) | LMNAMAPTSMOMIFALDH1A1 | |
| SCHEMBL5246999 | 0.91 | HDAC1 (0.46) | LMNAMAPTHDAC1EPHX2PPARG | |
| SCHEMBL5244694 | 0.90 | HPGD (0.48) | LMNAMAPTHDAC1SMN1; SMN2MIF | |
| SCHEMBL5245295 | 0.90 | LMNA (0.44) | LMNAMAPTSMOSMN1; SMN2EPHX2 | |
| SCHEMBL5246092 | 0.90 | EPHX2 (0.53) | LMNAL3MBTL1EPHX2 | |
| SCHEMBL5244366 | 0.89 | CCR1 (0.45) | LMNAMAPTALDH1A1 | |
| SCHEMBL5249263 | 0.89 | LMNA (0.45) | LMNAHDAC1SMOALDH1A1 | |
| SCHEMBL5244114 | 0.87 | CCR1 (0.43) | LMNAMAPTHDAC1ALDH1A1 | |
| SCHEMBL5248039 | 0.87 | EPHX2 (0.51) | LMNAL3MBTL1SMN1; SMN2EPHX2PPARG | |
| SCHEMBL5245644 | 0.87 | LMNA (0.41) | LMNAMAPTMIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |