Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGAV | P06756 | 6/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5247006 | 0.93 | TSHR (0.47) | TSHRMAPK10POLBMAPTSMN1; SMN2 | |
| SCHEMBL5246041 | 0.86 | MIF (0.45) | LMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5247737 | 0.85 | GLS (0.42) | POLBMAPTSMN1; SMN2KMT2AROCK2 | |
| Trifluoroacetic Acid SCHEMBL5244026 | 0.85 | MAPT (0.37) | TSHRMAPTKMT2ARAB9ALMNA | |
| Trifluoroacetic Acid SCHEMBL5244494 | 0.84 | MIF (0.37) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5248093 | 0.83 | ALDH1A1 (0.42) | TSHRMAPTROCK2LMNAKDM4E | |
| SCHEMBL5246315 | 0.82 | HPGD (0.39) | MAPTROCK2RAB9ALMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5246340 | 0.81 | NPC1 (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL5244350 | 0.81 | ROCK2 (0.38) | KMT2AROCK2LMNAALDH1A1 | |
| SCHEMBL5245310 | 0.81 | DRD2 (0.38) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |