Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249728 | 0.84 | GAA (0.53) | KDM4EALDH1A1HPGDKMT2AEGLN1 | |
| SCHEMBL5252061 | 0.78 | TNKS (0.53) | KDM4EALDH1A1HPGDKMT2AGLA | |
| SCHEMBL1664216 | 0.77 | KDM4E (0.97) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL5943243 | 0.75 | KDR (0.44) | KDM4EALDH1A1HPGDGAAHDAC8 | |
| SCHEMBL5252814 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL11839052 | 0.73 | ADORA3 (0.47) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL11829946 | 0.73 | GAA (0.50) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL8804615 | 0.72 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDKMT2AGLA | |
| SCHEMBL1192941 | 0.71 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL14022277 | 0.71 | PRMT5 (0.67) | KDM4EALDH1A1HPGDKMT2AHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | PFLUCKER FRANK | 2006-10-05 | — | — | US | disclosed |
| US-7101537-B2 | Tricyclic quinoxaline and quinoline derivatives as a UV filter | MERCK PATENTGESELLSCHAFT (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | KDM4E 1646/4885ALDH1A1 289/4885HPGD 237/4885 |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | RECQL, CUTA, NQO2 | KDM4E 1602/4885ALDH1A1 682/4885HPGD 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.