Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829946 | 0.88 | GAA (0.50) | GAANPC1RAB9ATNKSPARP1 | |
| SCHEMBL5252061 | 0.86 | TNKS (0.53) | GAANPC1RAB9ATNKSPARP1 | |
| SCHEMBL5249576 | 0.84 | KDM4E (0.61) | GAANPC1RAB9ATNKSPARP1 | |
| SCHEMBL11839052 | 0.84 | ADORA3 (0.47) | GAANPC1RAB9ATNKSPARP1 | |
| SCHEMBL5943243 | 0.82 | KDR (0.44) | GAANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5252814 | 0.82 | KDM4E (0.61) | GAANPC1RAB9ATNKSPARP1 | |
| SCHEMBL5251782 | 0.80 | MMP2 (0.63) | NPC1RAB9ATNKSPARP1TNKS2 | |
| SCHEMBL5250247 | 0.77 | HPGD (0.56) | GAANPC1RAB9ATNKSTNKS2 | |
| SCHEMBL5250588 | 0.76 | GUSB (0.62) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL5246817 | 0.75 | KDM4E (0.53) | GAANPC1RAB9AADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | PFLUCKER FRANK | 2006-10-05 | — | — | US | disclosed |
| US-7101537-B2 | Tricyclic quinoxaline and quinoline derivatives as a UV filter | MERCK PATENTGESELLSCHAFT (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | GAA 2632/4885NPC1 3313/4885RAB9A 1776/4885 |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | RECQL, CUTA, NQO2 | GAA 2272/4885NPC1 4215/4885RAB9A 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.