Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563999 | 0.81 | FFAR1 (0.60) | FFAR1PTGDR2ALDH1A1LMNATSHR | |
| SCHEMBL5250349 | 0.78 | FFAR1 (0.43) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL21376142 | 0.78 | FFAR1 (0.43) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL5542869 | 0.78 | FFAR1 (0.43) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL4299718 | 0.77 | ALDH1A1 (0.39) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL13918951 | 0.75 | FFAR1 (0.41) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL28586422 | 0.75 | FFAR1 (0.44) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL30270429 | 0.75 | CYP3A4 (0.53) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL27970953 | 0.75 | FFAR1 (0.55) | FFAR1PTGDR2ALDH1A1TDP1POLB | |
| SCHEMBL313726 | 0.75 | ALDH1A1 (0.40) | FFAR1PTGDR2ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039935-B | Piperidine antibiotics | ACTELION PHARMACEUTICALS LTD | 2011-04-20 | — | — | CN | disclosed |
| CN-101039935-A | Novel piperidine antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-19 | — | — | CN | disclosed |
| US-20070173532-A1 | New Piperidine Antibiotics | ACTELION PHARMACEUTICALS LTD. (CH) | 2007-07-26 | — | — | US | disclosed |
| EP-1799674-A1 | NEW PIPERIDINE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038172-A1 | NEW PIPERIDINE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173532-A1 | New Piperidine Antibiotics | OPRM1, SIGMAR1, CBR3 | FFAR1 2550/4885PTGDR2 2819/4885ALDH1A1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.