Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5249602 | 0.92 | LMNA (0.43) | LMNAHTTMAPK1SMN1; SMN2PTGER1 | |
| SCHEMBL5250048 | 0.91 | EPHX2 (0.46) | LMNASMN1; SMN2KMT2AHPGD | |
| Trifluoroacetic Acid SCHEMBL5246743 | 0.88 | MAPK14 (0.44) | LMNASMN1; SMN2PTGER1ALDH1A1KMT2A | |
| SCHEMBL5244539 | 0.87 | SMO (0.44) | LMNASMN1; SMN2MAPTKMT2AHPGD | |
| SCHEMBL5244893 | 0.87 | MAPK14 (0.48) | NAMPTRECQLIDH1 | |
| SCHEMBL5247431 | 0.86 | RIPK1 (0.44) | LMNASMN1; SMN2NAMPTKMT2AHPGD | |
| SCHEMBL5245587 | 0.85 | RAB9A (0.49) | LMNAKMT2A | |
| SCHEMBL5245586 | 0.85 | CCR1 (0.46) | LMNANAMPTMAPTKMT2AMMP13 | |
| SCHEMBL5249371 | 0.85 | CCR1 (0.49) | LMNAALDH1A1RECQLKMT2AHPGD | |
| SCHEMBL5244146 | 0.85 | CCR1 (0.42) | LMNASMN1; SMN2PTGER1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |