Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9763134 | 0.98 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL10404578 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL2133320 | 0.96 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL25283 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL4393614 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL26227 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| Lithium Ion SCHEMBL1457619 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| Silver SCHEMBL191053 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL20484784 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB | |
| SCHEMBL4966622 | 0.96 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112367849-A | Natural sweetness enhancer composition | 伊比西(北京)植物药物技术有限公司 | 2021-02-12 | — | — | CN | claimed |
| US-5723453-A | Stabilized, water-soluble aspirin composition | HEALTH CORPORATION (US) | 1998-03-03 | — | — | US | claimed |
| EP-0268616-A4 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION. | GALAT ALEXANDER | 1988-07-14 | — | — | EP | claimed |
| EP-0268616-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION. | GALAT ALEXANDER | 1988-06-01 | — | — | EP | claimed |
| WO-1987007264-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION | GALAT ALEXANDER (US) | 1987-12-03 | — | — | WO | claimed |
| JP-7330612-A | — | — | None | — | — | JP | disclosed |
| US-20240216318-A1 | TWO-COMPONENT COMPOSITION | ASAMEDIC AS (NO) | 2024-07-04 | — | — | US | disclosed |
| CN-117982446-A | Two-component composition | 阿萨德股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11918554-B2 | Two-component composition | ASAMEDIC AS (NO) | 2024-03-05 | — | — | US | disclosed |
| US-11850253-B2 | Two component compositions | ASAMEDIC AS (NO) | 2023-12-26 | — | — | US | disclosed |
| US-11844806-B2 | Compositions comprising acetylsalicylic acid and a phosphate salt | ASAMEDIC AS (NO) | 2023-12-19 | — | — | US | disclosed |
| CN-116332760-A | One-pot synthesis method of zinc acetylsalicylate | 河南省农业科学院植物保护研究所 | 2023-06-27 | — | — | CN | disclosed |
| EP-0268616-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION. | GALAT ALEXANDER | 1988-06-01 | — | — | EP | disclosed |
| EP-0268616-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION. | GALAT ALEXANDER | 1988-06-01 | — | — | EP | disclosed |
| WO-1987007264-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION | GALAT ALEXANDER (US) | 1987-12-03 | — | — | WO | disclosed |
| WO-1987007264-A1 | COMPOSITION OF MATTER CONTAINING POTASSIUM ACETYLSALICYLATE AND USEFUL FOR PRODUCING SOLUTIONS OF POTASSIUM ACETYLSALICYLATE, AND PROCESS FOR PREPARATION | GALAT ALEXANDER (US) | 1987-12-03 | — | — | WO | disclosed |
| US-4214183-A | DIELECTRIC CHARGE STORAGE LAYER CONTAINING RUBIDIUM OXIDE OR FRANCIUM OXIDE | OWENS-ILLINOIS, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4121133-A | Dielectric for multiple gaseous discharge display/memory panel having improved voltage characteristics | OWENS-ILLINOIS, INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4114064-A | MULTIPLE GASEOUS DISCHARGE DISPLAY/MEMORY PANEL HAVING IMPROVED VOLTAGE CHARACTERISTICS | OWENS-ILLINOIS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-3932920-A | MEMORY PANEL HAVING IMPROVED VOLTAGE CHARACTERISTICS | OWENS-ILLINOIS, INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850253-B2 | Two component compositions | PTGS2, PTGES2, PTGER2 | KDM4E 4138/4885ALDH1A1 465/4885HPGD 26/4885 |
| US-11844806-B2 | Compositions comprising acetylsalicylic acid and a phosphate salt | PAPSS1, APRT, ASAH2 | KDM4E 4402/4885ALDH1A1 499/4885HPGD 49/4885 |
| US-11918554-B2 | Two-component composition | PTGER2, PTGS2, PTGES2 | KDM4E 4472/4885ALDH1A1 559/4885HPGD 45/4885 |
| US-20240216318-A1 | TWO-COMPONENT COMPOSITION | PTGS2, PTGER2, PTGES2 | KDM4E 4746/4885ALDH1A1 462/4885HPGD 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.