SCHEMBL9769436

SCHEMBL9769436

[O-][n+]1c(C(Cl)(Cl)Cl)ncc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769252 0.84 ATM (0.45) ATMNPC1RAB9A
SCHEMBL5259264 0.76 ATM (0.48) ATMNPC1RAB9A
SCHEMBL4559941 0.72 ATM (0.48) ATMNPC1RAB9A
SCHEMBL4620642 0.72 ATM (0.48) ATMNPC1RAB9A
SCHEMBL3535166 0.72 ATM (0.48) ATMNPC1RAB9A
SCHEMBL8424490 0.72 ATM (0.48) ATMNPC1RAB9A
SCHEMBL5250885 0.69 ATM (0.45) ATMNPC1RAB9A
SCHEMBL400031 0.68 ATM (0.40) ATMNPC1RAB9A
SCHEMBL8626591 0.68 ATM (0.40) ATMNPC1RAB9A
SCHEMBL8423013 0.68 ATM (0.44) ATMNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
US-4584260-A 4,41-BIS(DIALKYLAMINO)BENZOPHENONE A BENZOPHENONE, 1,3,4-OXADIAZOLE COMPOUND, AROMATIC HALOGENATED SULFONE, QUINAZOLINE AND TRIAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1986-04-22 US disclosed