Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250885 | 0.72 | ATM (0.45) | ATMKDM4EGPR3 | |
| SCHEMBL3111168 | 0.70 | ATM (0.40) | ATMKDM4E | |
| SCHEMBL4559941 | 0.64 | ATM (0.48) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL8424490 | 0.64 | ATM (0.48) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL3535166 | 0.64 | ATM (0.48) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL4620642 | 0.64 | ATM (0.48) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL5259264 | 0.64 | ATM (0.48) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL29359446 | 0.62 | CRHBP (0.61) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL51330 | 0.62 | CRHBP (0.61) | ATMCRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL9769252 | 0.62 | ATM (0.45) | ATMKDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392645-A2 | AZA HYDROXYLATED ETHYL AMINE COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002094768-A2 | AZA HYDROXYLATED ETHYL AMINE COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2002-11-28 | — | — | WO | disclosed |